Translating evidence into global impact: lessons for HIV research and policy development from the AMBITION trial.
Authors

Jarvis JN, Chou R, Harrison TS, Lawrence DS, Muthoga C, Mupeli K, Meya DB, Mwandumba HC, Kanyama C, Meintjes G, Leeme TB, Ndhlovu CE, Beattie P, Sued O, Pérez Casas C, Makanga M, Ford N.

Journal : Lancet Glob Health.

DOI : 10.1016/S2214-109X(23)00412-6.

PMCID : PMC7615252

PMID : 37858577

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Safety of AZD1222 COVID-19 vaccine and low Incidence of SARS-CoV-2 infection in Botswana following ChAdOx1(AZD1222) vaccination: A single-arm open-label interventional study - final study results.
Authors
Makhema J, Shava E, Izu A, Gaolathe T, Kuate L, Walker A, Carty L, Georgiou P, Kgathi C, Choga WT, Sekoto T, Seonyatseng N, Mogashoa T, Maphorisa CN, Mohammed T, Ntalabgwe T, Frank TT, Matlhaku B, Diphoko A, Phindela T, Kaunda A, Kgari P, Kanyakula T, Palalani G, Phakedi I, Mmalane M, Taylor S, Moyo S.

Journal : IJID Reg.

DOI : 10.1016/j.ijregi.2023.11.002.

PMCID : PMC10714336

PMID : 38090729

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Cryptococcal meningitis.
Authors
Tugume L, Ssebambulidde K, Kasibante J, Ellis J, Wake RM, Gakuru J, Lawrence DS, Abassi M, Rajasingham R, Meya DB, Boulware DR.

Journal : Nat Rev Dis Primers.

DOI : 10.1038/s41572-023-00472-z.

PMID : 37945681

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The impact of free antiretroviral therapy for pregnant non-citizens and their infants in Botswana.
Authors
Fennell C, Escudero D, Zash R, Diseko M, Mayondi G, Mabuta J, Sekoto T, Gaolathe T, Mmalane M, Lockman S, Makhema J, Shapiro R. J

Journal : Int AIDS Soc.

DOI : 10.1002/jia2.26161.

PMCID : PMC10603275

PMID : 37885157

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Predicted resistance to broadly neutralizing antibodies (bnAbs) and associated HIV-1 envelope characteristics among seroconverting adults in Botswana.
Authors
Moraka NO, Choga WT, Pema MN, Chawawa MK, Gobe I, Mokomane M, Bareng OT, Bhebhe L, Kelentse N, Mulenga G, Pretorius Holme M, Mohammed T, Koofhethile CK, Makhema JM, Shapiro R, Lockman S, Moyo S, Gaseitsiwe S.

Journal : Sci Rep.

DOI : 10.1038/s41598-023-44722-2.

PMCID : PMC10598268

PMID : 37875518

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T-SPOT.TB reactivity in Southern African children with and without in utero HIV exposure
Authors
Iwase SC, Edlefsen PT, Bhebhe L, Motsumi K, Moyo S, Happel AU, Shao D, Mmasa N, Schenkel S, Gasper MA, Dubois M, Files MA, Seshadri C, Duffy F, Aitchison J, Netea MG, Jao J, Cameron DW, Gray CM, Jaspan HB, Powis KM.

Journal : Clin Infect Dis.

DOI : doi: 10.1093/cid/ciad356

PMID : 37293702

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Fostemsavir resistance-associated polymorphisms in HIV-1 subtype C in a large cohort of treatment-naïve and treatment-experienced individuals in Botswana.
Authors
Zuze BJL, Radibe BT, Choga WT, Bareng OT, Moraka NO, Maruapula D, Seru K, Mokgethi P, Mokaleng B, Ndlovu N, Kelentse N, Pretorius-Holme M, Shapiro R, Lockman S, Makhema J, Novitsky V, Seatla KK, Moyo S, Gaseitsiwe S.

Journal : Microbiol Spectr.

DOI : 10.1128/spectrum.01251-23.

PMID : 37823653

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Reduction in mortality from HIV-related CNS infections in routine care in Africa (DREAMM): a before-and-after, implementation study.
Authors
Mfinanga S, Kanyama C, Kouanfack C, Nyirenda S, Kivuyo SL, Boyer-Chammard T, Phiri S, Ngoma J, Shimwela M, Nkungu D, Fomete LN, Simbauranga R, Chawinga C, Ngakam N, Heller T, Lontsi SS, Aghakishiyeva E, Jalava K, Fuller S, Reid AM, Rajasingham R, Lawrence DS, Hosseinipour MC, Beaumont E, Bradley J, Jaffar S, Lortholary O, Harrison T, Molloy SF, Sturny-Leclère A, Loyse A; DREAMM Consortium.

Journal : Lancet HIV.

DOI : 10.1016/S2352-3018(23)00182-0.

PMID : 37802567

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Incidence and Predictors of Pregnancy in Women Enrolled in Large Multi-National HIV Treatment Trials of the AIDS Clinical Trials Group.
Authors
Omoz-Oarhe AE, Hughes MD, Bao Y, Short WR, Mngqibisa R, Cohn SE, Weinberg A, Rosa A, Collier A, Samaneka W, Morroni C, Lockman S.

Journal : J Acquir Immune Defic Syndr.

DOI : 10.1097/QAI.0000000000003299

PMID : 37820116

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Timing of maternal isoniazid preventive therapy on tuberculosis infection among infants exposed to HIV in low-income and middle-income settings: a secondary analysis of the TB APPRISE trial.
Authors
Gupta A, Singh P, Aaron L, Montepiedra G, Chipato T, Stranix-Chibanda L, Chanaiwa V, Vhembo T, Mutambanengwe M, Masheto G, Raesi M, Bradford S, Golner A, Costello D, Kulkarni V, Shayo A, Kabugho E, Jean-Phillippe P, Chakhtoura N, Sterling TR, Theron G, Weinberg A; IMPAACT P1078 TB APPRISE Study Team.

Journal : Lancet Child Adolesc Health.

DOI : 10.1016/S2352-4642(23)00174-8.

PMID : 37634517

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One Week of Oral Camostat Versus Placebo in Nonhospitalized Adults With Mild-to-Moderate Coronavirus Disease 2019: A Randomized Controlled Phase 2 Trial.
Authors
Jilg N, Chew KW, Giganti MJ, Daar ES, Wohl DA, Javan AC, Kantor A, Moser C, Coombs RW, Neytman G, Hoover K, Jana A, Hart PA, Greninger AL, Szurgot B, Eron JJ, Currier JS, Hughes MD, Smith DM, Li JZ; ACTIV-2/A5401 Study Team.

Journal : Clin Infect Dis.

DOI : 10.1093/cid/ciad342.

PMID : 37279602

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The case for precision medicine in the prevention, diagnosis, and treatment of cardiometabolic diseases in low-income and middle-income countries.
Authors
Misra S, Aguilar-Salinas CA, Chikowore T, Konradsen F, Ma RCW, Mbau L, Mohan V, Morton RW, Nyirenda MJ, Tapela N, Franks PW.

Journal : Lancet Diabetes Endocrinol.

DOI : doi: 10.1016/S2213-8587(23)00164-X

PMID : 37804857

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Archived rilpivirine-associated resistance mutations among ART-naive and virologically suppressed people living with HIV-1 subtype C in Botswana: implications for cabotegravir/rilpivirine use.
Authors
Maruapula D, Moraka NO, Bareng OT, Mokgethi PT, Choga WT, Seatla KK, Kelentse N, Koofhethille CK, Zuze BJL, Gaolathe T, Pretorius-Holme M, Makhema J, Novitsky V, Shapiro R, Moyo S, Lockman S, Gaseitsiwe S.

Journal : J Antimicrob Chemother.

DOI : 10.1093/jac/dkad258

PMID : 37585352

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Pathways and Intersections: Multifaceted Approaches to Engage Individuals From Underrepresented and Marginalized Communities in HIV Research and Career Development.
Authors
Irie WC, Chitneni P, Glynn TR, Allen W, Chai PR, Engelman AN, Hurtado R, Li JZ, Li P, Lockman S, Marcus JL, Ogunshola FJ, Rönn MM, Haberer J, Ghebremichael M, Ciaranello A; Harvard University Center for AIDS Research Diversity, Equity, and Inclusion Working Group.

Journal : J Acquir Immune Defic Syndr.

DOI : doi: 10.1097/QAI.0000000000003265

PMCID : PMC10503030

PMID : 37707858

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Adverse Pregnancy Outcomes among HIV-infected Women Taking Isoniazid Preventive Therapy During the First Trimester.
Authors
Gupta A, Hughes MD, Cruz JL, Avihingsanon A, Mwelase N, Severe P, Omoz-Oarhe A, Masheto G, Moran L, Benson CA, Chaisson RE, Swindells S.

Journal : Clin Infect Dis.

DOI : 10.1093/cid/ciad583

PMID : 37768207

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