Study Objectives

Study Objectives: To conduct a comprehensive assessment of preferences for pre-exposure prophylaxis (PrEP) delivery among pregnant and breastfeeding women not living with HIV in Gaborone.  

Study Design: Cross-sectional, mixed methods 

Principal Investigator: Ava Avalos, MD

Study Objectives

Primary Objectives

Study Objectives:

Principal Investigator - Professor Mosepele Mosepele MD, MSc

Study Objectives

Primary Objectives:

1. To evaluate SARS-CoV-2-specific qualitative antibody responses after the administration of full vaccination doses (either single or second doses) of vaccines in Botswana.
2. To evaluate SARS-CoV-2-specific quantitative antibody responses after the administration of full doses of vaccines in Botswana.

Secondary Objectives:

Principal Investigator - Professor Mosepele Mosepele, MD, MSc

Study Status: The study opened on January 22, 2020 and accrual completed on January 27, 2021. Participant follow up ongoing.

Study Objectives:

Principal Investigators - Dr. Sikhulile Moyo, MSc, MPH, PhD | Dr. Catherine K. Koofhethile, PhD

Study Objectives:  This study has two main goals:

Principal Investigator - Professor Roger L. Shapiro, MD, MPH

Study Objectives

Primary Objectives

Principal Investigator: Rebecca Luckett MD MPH

Study Objectives

Objective 1: Improve the quality of decision making around caesarean section

Principal Investigator - Dr. Scott Dryden-Peterson MD, MSc

Study Objectives

Aim 1: The study will compare the LVEF between patients with and without HIV  who are being treated with anthracyclines. We hypothesize that the LVEF will be  lower after anthracycline among individuals living with HIV.

Principal Investigator - Dr. Chelsea Morroni, MD, MPH, PhD

Name of the Study: The Contraceptives and Dolutegravir-based ART (CODA) Study

Study Status: Recruiting 

Study Objectives:

Study Objectives: To determine the acceptability, feasibility, and costs of implementing point-of-care syphilis testing and treatment among pregnant women in Gaborone, Botswana.

Study Design: Cohort study

Principal Investigator - Professor Roger L. Shapiro, MD, MPH

Study Objectives

The overall objective of the EIT study is to determine whether very early antiretroviral treatment (ART) initiation in HIV-infected infants limits the seeding of viral reservoirs and maintains immune responses, potentially allowing future periods off ART.

Specific Aims: 

Study Objectives

Principal Investigator: Roxanna Haghighat, DPhil | Kathleen Powis, MD, MPH, MBA

Study Objectives

Principal Investigator - Nabila Youssouf PhD | Laura Bogart | Mosepele Mosepele MD, MSc

Name of the Study: Exploring the Acceptability and Feasibility of COVID19 Testing among Truck Drivers in Botswana

Study Status: Completed recruitment – data analysis ongoing

Study Objectives: To explore the acceptability and feasibility on COVID 19 testing among truck drivers entering Botswana and to acquire feedback about potential interventions to further respond to this evolving crisis. 

Principal Investigator - Dr. Scott Dryden-Peterson, MD, MSc

Principal Investigators - Dr. Kathleen M. Powis, MD, MPH, MBA | Dr. Jennifer Jao, MD, MPH | Dr. Joseph Makhema, MB.ChB, FRCP

Study Objectives 

Primary Study Aims

Principal Investigator - Dr. Scott Dryden-Peterson MD, MSc

Thabatse is a prospective cohort study which aims to evaluate the risk factors for cancer and describe the response to treatment for patients who are HIV positive and not on Antiretroviral Therapy (ART) and those on ART.

Study Objectives

The primary aims are to evaluate the important risk factors for cancer in Botswana (including HIV) and describe the response to treatment for patients without HIV, with HIV but not yet on HAART, and those with HIV and on HAART.

Principal Investigator - Dr. Rebecca Luckett, MD, MPH

Name of the Study: Evaluation of cervical cancer screening algorithms using primary high risk human papillomavirus (HPV) in Gaborone and South East District, Botswana

Completed: Recruitment of 300 women living with HIV in Gaborone, and one year follow-up of this cohort. 

On-going: Recruitment of a new cohort of 3000 women in South East District is currently underway. 50% of the cohort will be women living with HIV.